Cerebrum Labeling – alignwarp error

Forums Forums Cortical Surface Extraction Cerebrum Labeling – alignwarp error

This topic contains 2 replies, has 3 voices, and was last updated by  KeiraKay 2 years, 1 month ago.

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  • #575



    I have been running the cerebrum labeling step for several subjects, and I have been getting this warning for some of them:

    Performing warp alignment (order=5) of atlas brain to subject brain
    alignwarp.c: 262: WARNING: Registration terminated due to a Hessian matrix that was not positive definite
    Inspection of results is advised

    I get this warning in the GUI as well as the command line. Does anyone know if there’s a way to fix this issue?

    Thank you,


  • #576

    Anand Joshi

    You should check the outputs in case of this warning. Please check outputs at steps 22 and 23 at the following link:
    especially check the green curve showing the cerebrum mask.

    Please make sure that your outputs look like that. If they do, then you can ignore the warning.

  • #1145


    Thanks for sharing this.

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