[Louise]

Hi Anand Joshi,
thank you for your fast answer. And sorry for the missing image. I try to repost it now.

Left Lateral Orbitofrontal Gyrus

I am not sure if I get you right. In my understanding you told me to extract total brain surface like *.hemi.mid.cortex.svreg.dfs. And then smooth it and extract features with matlab. The problem is, that I try to get closed surfaces and if I extract different anatomical structures from the *.hemi.mid.cortex.svreg.dfs file they are not closed.

The smoothing problem only appears if if I use *.svreg.label.nii.gz volumes to calculate self generated surfaces. And this is the way the image I uploaded is generated.

Is there any possibility to extract closed surfaces from single anatomical structures by using the command line?
Greetings Louise

• This reply was modified 7 years ago by Louise.

[Louise]

Thank you for your fast answer. I tried to combine GM and WM now and it looks a bit better. Nevertheless the result seems to be a little edgy for me. Furthermore there are some small disjointed parts, as you can see in the image.

Maybe I can handle this by smoothing the surface.

My goal is to compute some shape features like total curvature and maybe some others. When I look at the surface model in *.hemi.mid.cortex.svreg.dfs it looks smooth so I hoped to get such an accurate model as well to increase the accuracy of my features.

Greetings Louise

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