One of the unique features of BrainSuite is that the volumetric registration used is ‘surface constrained volumetric registration’. This means that during the registration process, cortical surface and subcortical structures are aligned simultaneously leading to a consistent registration.
Another unique feature is that the cortical thickness analysis used in BrainSuite uses computation of cortical thickness using partial tissue fraction information.
For the subcortex, the total volumes of various structures, as well as gray matter and white matters, are reported in detail by BrainSuite. I am not aware of any other functionality that other software has and is missing in BrainSuite for structural analysis.
